Late Relapsing Childhood Lymphoblastic Leukemia
نویسندگان
چکیده
منابع مشابه
Late relapsing childhood lymphoblastic leukemia.
Childhood lymphoblastic leukemia (ALL) is usually assumed to have been permanently eradicated in patients in long-term remission, but occasionally can recur after many years. To learn more about the problem, we studied a group of children whose leukemia had been in remission for 10 or more years before relapse and tried to determine whether they had true recurrences or second malignancies. We s...
متن کاملLate relapse in a case of childhood acute lymphoblastic leukemia.
A 14-year-old boy presented first at the age of 5 years in May 1985 with complaints of low backache for 3.5 months, fever for 3 weeks and epistaxis for 10 days. The child was found to have marked pallor, sternal tenderness with no significant lymphadenopathy. No hepatosplenomegaly was found. He had a hemoglobin of 95 g/L; total leukocyte count (TLC) 5000/mm and platelets 60,000/mm with a normal...
متن کاملChildhood Acute Lymphoblastic Leukemia.
The cure rate for childhood acute lymphoblastic leukemia (ALL) now exceeds 70%. This success has been achieved in part by improvements in the biologic characterization of newly diagnosed patients. Modern treatment protocols rely on this information to tailor therapy to a patient's risk of relapse. Patients with favorable genetic features, such as hyperdiploidy or the TEL-AML1 fusion, can be tre...
متن کاملChildhood Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is recognized as a fast-developing cancer originated from blood-progenitor cells. Blasts cells are immature cells which generate white blood cells (leukocytes), and it is the malignancy of the blast cells which lead to leukemias. The bone marrow is gradually filled up with these blasts and as a result, the production of healthy blood cells will be damaged. Mal...
متن کاملMorphological metamorphosis in relapsing lymphoblastic leukemia.
Blast cell morphology was assessed at diagnosis and subsequent bone marrow relapse in 33 unselected patients with lymphoblastic leukemia (ALL). Each marrow was classified 'blind' according to the French-American-British (FAB) criteria, and it was found that 19 of 24 (79%) patients initially typed as FAB L1 changed to FAB L2 during the course of their disease, but no patient made the reverse mor...
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ژورنال
عنوان ژورنال: Blood
سال: 1998
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v92.7.2334